{"id":9097,"date":"2019-02-26T14:23:47","date_gmt":"2019-02-26T14:23:47","guid":{"rendered":"https:\/\/staging.futurehealthbiobank.com\/qa-en\/?p=9097"},"modified":"2019-02-26T14:23:47","modified_gmt":"2019-02-26T14:23:47","slug":"cord-blood-stem-cell-transplant-corrects-irritable-bowel-disease","status":"publish","type":"post","link":"https:\/\/staging.futurehealthbiobank.com\/qa-en\/blog\/cord-blood-stem-cell-transplant-corrects-irritable-bowel-disease\/","title":{"rendered":"Cord Blood Stem Cell Transplant Corrects Irritable Bowel Disease"},"content":{"rendered":"

A baby girl, Zhao Jiaxin, has become the first child in China to receive a cord blood stem cell transplant to cure an inherited type of Irritable Bowel Disease.<\/h3>\n

<\/p>\n

When Zhao was born in 2015, she started suffering from fever and diarrhoea from just 8 days old. Her older sister had the same symptoms and tragically died at 5 months old, so her parents feared they might lose Zhao too. So, they turned to the Children\u2019s Hospital of Fudan University in Shanghai.<\/p>\n

At the University, the family found out that Zhao had a Very Early Onset form of Irritable Bowel Disease (VEO-IBS); a rare condition caused by an inherited genetic mutation. The deficiency in the defective gene led to severe problems with Zhao\u2019s immune system, which cause malnourishment, intestinal abscesses and fistulas.<\/p>\n

The only effective treatment is a stem cell transplant\u2026 It can help to repair the genetic deformity and control the symptoms of the disease<\/p><\/blockquote>\n

– Huang Ying, MD PhD, Children\u2019s Hospital of Fudan University<\/cite><\/p>\n

In 2015, Zhao became one of very few babies to receive a cord blood stem cell transplant for VEO-IBS with IL10RA immune deficiency. The successful transplants were carried out using low-intensity chemotherapy conditioning, with positive results within 1-3 months. Thanks to this pioneering transplant, Zhao\u2019s condition has improved greatly and she should lead a happy, healthy life.<\/p>\n

Reference: parentsguidecordblood.org\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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