{"id":9275,"date":"2019-03-28T10:21:39","date_gmt":"2019-03-28T09:21:39","guid":{"rendered":"https:\/\/staging.futurehealthbiobank.com\/si\/?p=9275"},"modified":"2019-03-28T10:21:39","modified_gmt":"2019-03-28T09:21:39","slug":"po-terapiji-z-maticnimi-celicami-spet-uporablja-roke-in-dlani","status":"publish","type":"post","link":"https:\/\/staging.futurehealthbiobank.com\/si\/blog\/po-terapiji-z-maticnimi-celicami-spet-uporablja-roke-in-dlani\/","title":{"rendered":"Po terapiji z mati\u010dnimi celicami spet uporablja roke in dlani"},"content":{"rendered":"

Leta 2016 je Kris Boesen do\u017eivel hudo po\u0161kodbo hrbtenja\u010de, takrat je bil star 20 let. Do po\u0161kodbe je pri\u0161lo v hudi avtomobilski nesre\u010di v Bakersfield, ZDA, po kateri je bil paraliziran od vratu navzdol. Po\u0161kodba je bila trajna in bil je obsojen na do\u017eivljenjsko paralizo.<\/h3>\n

<\/p>\n

Star\u0161i so dobili novo upanje, ko je bil Kris ustrezen kandidat za klini\u010dno \u0161tudijo v Keck Medical Centre, Univerze v Kaliforniji. \u0160tudija je vklju\u010devala vbrizganje pripravka z mati\u010dnim celicam neposredno v hrbtenja\u010do.<\/p>\n

Ta terapija z mati\u010dnimi celicami je znana kot AST-OPC1 in ima sposobnost razvoja in za\u0161\u010dite \u017eiv\u010dnih celic v centralnem \u017eiv\u010dnem sistemu. Tako pride do zdravljenja po\u0161kovbe na hrbtenja\u0161i pri po\u0161kodovanih bolnikih.<\/p>\n

Obi\u010dajno so bolniki s po\u0161kodbo hrbtenja\u010de podvr\u017eeni operaciji, ki stabilizira hrbtenico, ampak ne povrne motori\u010dnih ali senzori\u010dnih funkcij\u2026S to \u0161tudijo testiramo postopek, ki lahko izbolj\u0161a nevrolo\u0161ke funkcije. To pomeni, da namesto do\u017eivljenjske paralize lahko pride do uporabe rok oz. dlani. Vzpostavitev tega nivoja funkcije lahko bistveno izbolj\u0161a vsakodnevno \u017eivljenje bolnikov s hudo po\u0161kodbo hrbtenja\u010de.<\/p><\/blockquote>\n

– Charles Liu, Director of the USC Neurorestoration Center<\/cite><\/p>\n

Dva tedna po posegu se je Krisovo stanje za\u010delo izbolj\u0161ati. Po treh mesecih je ponovno imel povrnjene motori\u010dne in senzori\u010dne funkcije v rokah in dlaneh. Ponovno je lahko uporabljal telefon, pisal, sam premikal vozi\u010dek in nasploh imel ve\u010djo neodvisnost.<\/p>\n

V \u0161tudiji je sodelovalo 25 bolnikov, ni bilo zaznani nobenih resnih stranskih u\u010dinkov. MRI testi so pri 95 % bolnikov pokazal razvoj tkivnega matriksa na mestu po\u0161kodbe, kar pomeni da so se vbrzgane mati\u010dne celice za\u010dele razra\u0161\u010dati.<\/p>\n

Za enkrat niti Kris niti ostali bolniki niso \u0161e sposobni hoditi, vendar je uspeh te \u0161tudije odli\u010den primer, kako imajo mati\u010dne celice potencial za izbolj\u0161anje kvalitete \u017eivljenja bolnikov z po\u0161kodbo hrbtenja\u010de.<\/p>\n

Kvalificirani bolniki za to klini\u010dno \u0161tudijo v fazi 1\/2 so bolniki med starostjo 18-69 let, s stabilno po\u0161kodbo, da lahko prejmejo terapijo mati\u010dnih celic, 14 – 30 dni po po\u0161kodbi.<\/p>\n

References:
\nnews.usc.edu\/<\/a>
\nblog.cirm.ca.gov\/tag\/kris-boesen\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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